Intracystic Papillary Carcinoma in Male Breast with High Nuclear Grade: A Case Report
Published: August 1, 2015 | DOI: https://doi.org/10.7860/JCDR/2015/.6299
Abdulaziz Ajlan M. Al Salloom
1. Consultand and Assistant Professor, Department of Pathology, College of Medicine, Qassim University, Buraidah, KSA, Saudi Arabia.
Correspondence
Dr. Abdulaziz A.M. Al Salloom,
Consultand and Assistant Professor, Department of Pathology, College of Medicine, Qassim University,
PO. Box 6655, Buraidah-51452, Saudi Arabia.
E-mail: a.alsalloom@qumed.edu.sa
Intracystic papillary carcinoma (IPC) in men is an extremely rare disease that accounts for less than 1% of all malignancies with only a few case presentations published so far. This report presents a case of 53-year-old male, who presented a painless swelling of his left breast. The left breast mass was 6 cm maximally and was found to be non-invasive IPC. The tumour is consistently positive for GCDFP-15, ER or PR and negative for HER-2. It consists of predominantly fibrovascular stromal lined by monotonous epithelial cells retaining intermediate to high histological grade with a high nuclear cytoplasmic ratio. In addition, increased numbers of mitotic figures were also seen. Chest X-ray, liver ultrasound and bone centigram showed no evidence of distant metastases. In short, this is the first case report from Saudi Arabia of a male having IPC, with increased number of mitotic figures and high nuclear grades.
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